According to several modern analyses, probably Columbus died of Reiter's Syndrome, an outlandish illness. Christopher Columbus dies On May 20, 1506, the great Italian explorer Christopher Columbus dies in Valladolid, Spain. His illness was a painful one. His real name in Italian was Cristoforo Colombo; his name in Spanish was Cristóbal Colón.. Columbus died on 20 May 1506, in Valladolid, Spain. When the Spanish learned that Columbus had found a New World, many other people, called conquistadors, went there too. On May 11, 1502, Christopher Columbus set out on his fourth and final voyage to the New World with a fleet of four ships. Famous explorer Christopher Columbus, whom the U.S. celebrates today with “Columbus Day,” died at age 54 in 1506 after battling "reactive arthritis," an illness which is now treatable. After two years of his final voyage, he died on May 20, 1506. His mission was to explore uncharted areas to the west of the Caribbean in hopes of finding a passage to the Orient. Christopher Columbus died on May 20, 1506 at only 55 years of age due to heart failure. Quick Facts Name Christopher Columbus Birth Date c. October 31, 1451 Death Date May 20, 1506 Did You Know? He died in a place called Valladolid, Spain when he was Fifty … Quick Facts Name Christopher Columbus Birth Date c. October 31, 1451 Death Date May 20, 1506 Did You Know? In 1492 Columbus landed on an island of the Bahamas, the first European to do so.His initial goal was to find … Christopher Columbus: Early Life . Bartholomew Columbus, Italian explorer, brother of Christopher Columbus, accomplished cartographer and cosmographer, and probably collaborator on his brother’s project to sail around the world. Where Did Christopher Columbus Die There are crucial issues regarding the death of Christopher Columbus. His exploration of these areas paved the way for European colonization. Columbus was the first European to … In 1484, according to tradition, he visited Henry VII of England and gave him a map of the world, showing Columbus estimated the earth to … This led to the Spanish colonization of the Americas. He had suffered through a long terminal illness that first showed symptoms on his third voyage eight years before. Christopher Columbus died in Valladolid, Spain, on May 20, 1506, at the age of 54. 20 May 1506 in Valladolid, Spain. Christopher Columbus was born on August 25 1451 in Genoa Italy and died on May 20, 1506 outside of Valladolid, Spain. After the death of Columbus, Diego inherited the title of Admiral of the Indies. Modern doctors believe he suffered from Reiter's Syndrome, or reactive arthritis, an illness caused by intestinal bacterial infections or sexually transmitted diseases like gonorrhea.

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